Semester : Semester I 2010/2011 _______________________________________________________________________ Lecturer :Nik Ahmad Nizam Bin Nik Malek _______________________________________________________________________ Synopsis :

This subject focuses on basic and fundamental theory in bio-organic chemistry. Bio-organic chemistry is the knowledge of organic chemistry for the biology major. The fundamental of organic chemistry is essential prior to understanding the biochemistry and biomolecules since each of biological compound comprise of organic molecules. An introduction of this subject includes fundamental of the framework of organic compounds and their functional groups. The topic on the basic structure of biological compounds such as proteins, carbohydrates, nucleic acid and lipids is enclosed.

_______________________________________________________________________ This work, SQG1603 Bioorganic Chemistry by Nik Ahmad Nizam Bin Nik Malek is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License
Lesson 1

Introduction

Why a biologist needs to learn and understand organic chemistry? Why organic chemistry is so important to the biologist? The answer on this issue is discussed in the first note (Introduction).

Lesson 2

Introduction to Organic Chemistry

• Characteristic features of organic compounds
• Drawing organic compounds

Lesson 3 (Part 1)

Alkanes

HYDROCARBON
· Alkane
o Classification
o Nomenclature
o Structural isomers
o Physical properties

Lesson 3 (Part 2)

Alkenes, Alkynes and Aromatic

HYDROCARBON
· Alkene, alkyne and aromatic
o Nomenclature
o Geometric isomer
o Reaction
o Fundamental of conjugated system (benzene)

Lesson 4

Organic Compounds Containing Oxygen

FUNCTIONAL GROUPS
ORGANIC COMPOUNDS CONTAINING OXYGEN
o List of Functional group
o Naming, reaction and physical properties of
o Alcohols
o Ethers
o Aldehydes and ketones
o Carboxylic acis
o Esters

Lesson 5

Organic Compounds Containing Nitrogen

FUNCTIONAL GROUPS
ORGANIC COMPOUNDS CONTAINING NITROGEN
o Naming, reaction and physical properties of
o Amines
o Amides

Lesson 6

Other Organic Compounds

FUNCTIONAL GROUPS
OTHER ORGANIC COMPOUNDS
o Alkyl halides
o Thiols
o Phosphate

Lesson 7

Basic Compounds In Biomolecules : Amino Acid In Protein

BASIC COMPOUNDS IN BIOMOLECULES
AMINO ACIDS (PROTEIN)
o Basic structure f amino acids
o Functional group in amino acids
o Enantiomer
o Acid base behavior of amino acids

Lesson 8

Basic Compounds In Biomolecules : Saccharides In Carbohydrate

BASIC COMPOUNDS IN BIOMOLECULES
SACCHARIDES (CARBOHYDRATE)
o Classification f monosaccharides
o Enantiomer
o Cyclic form

Lesson 9

Basic Compounds In Biomolecules : Nucleic Acids

BASIC COMPOUNDS IN BIOMOLECULES
NUCLEIC ACIDS (DNA AND RNA)
o Nucleoside
o Monosaccharide
o Bases
o Nucleotide

Lesson 10

Basic Compounds In Biomolecules : Lipids

BASIC COMPOUNDS IN BIOMOLECULES
LIPIDS
o Triacylglycerols
o Fatty acids
o Phospholipids
o Phosphoacylglycerols